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Glaucoma

Case 9

Patient Presentation: A 49-year-old myopic female with family history of primary open angle glaucoma (POAG) was referred by her optometrist with concern for glaucoma. Visual acuity was 20/20-1 OD and 20/20 OS. IOP was 20 mmHg OD and 26 mmHg OS. CCT was 560 μm OD and 545 μm OS. Scleral spur was visualized 360 degrees bilaterally on gonioscopy.

OCT ONH/RNFL and ganglion cell analysis (GCA) were performed and are shown below:

Glaucoma_9_1.png
Glaucoma_9_2.png

Question 1: What is the MOST accurate interpretation of the RNFL and GCA OCT findings?

Question 2: How would you best classify this patient’s left eye based on the provided OCT and visual field findings?

Question 3: How could you best manage this patient’s left eye? 

References:

  1. Kass MA, Heuer DK, Higginbotham EJ, et al. The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120(6):701-830. doi:10.1001/archopht.120.6.701

  2. Gordon MO, Beiser JA, Brandt JD, et al. The Ocular Hypertension Treatment Study: Baseline Factors That Predict the Onset of Primary Open-Angle Glaucoma. Arch Ophthalmol. 2002;120(6):714–720. doi:10.1001/archopht.120.6.71

​Learning Objectives:

  1. Differentiate ocular hypertension from established glaucoma by integrating intraocular pressure, OCT structural findings, and visual field testing.

  2. Apply risk-based clinical reasoning to determine when close observation versus intervention is appropriate in patients with ocular hypertension.

  3. Apply findings of the Ocular Hypertension Treatment Study into clinical practice.

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