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Retina

Case 83

Patient presentation: A 68-year-old pseudophakic man was referred to a tertiary retina clinic for blurred vision and abnormal OCT findings. BCVA was 20/25 OU. Intraocular pressure was within normal limits and there was no RAPD. Fundus photograph and OCT macula OU were performed and shown below.

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Question 1: What layer is the abnormal finding present in?

Question 2: What is the diagnosis?

Question 3: What are some common associations with reticular pseudodrusen?

References:

  1. Agrón E, Domalpally A, Cukras CA, Clemons TE, Chen Q, Lu Z, Chew EY, Keenan TDL; AREDS and AREDS2 Research Groups. Reticular Pseudodrusen: The Third Macular Risk Feature for Progression to Late Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report 30. Ophthalmology. 2022 Oct;129(10):1107-1119. doi: 10.1016/j.ophtha.2022.05.021. Epub 2022 May 31. PMID: 35660417; PMCID: PMC9509418.

  2. Cleland SC, Domalpally A, Liu Z, Pak JW, Blodi BA, Bailey S, Gehrs K, Wallace R, Tinker L, Mares JA; Second Carotenoids in Age-Related Eye Disease Study Investigators. Reticular Pseudodrusen Characteristics and Associations in the Carotenoids in Age-Related Eye Disease Study 2 (CAREDS2), an Ancillary Study of the Women's Health Initiative. Ophthalmol Retina. 2021 Aug;5(8):721-729. doi: 10.1016/j.oret.2020.12.019. Epub 2020 Dec 30. PMID: 33387684; PMCID: PMC8243566.

Learning Objectives:

  1. To diagnose and classify reticular pseudodrusen using OCT findings.

  2. To understand the associations of reticular pseudodrusen.

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